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Semaglutide

GLP-1 Receptor Agonist

FDA-approved GLP-1 agonist. The most-studied weight management peptide.

Weight researchDiabetes researchMetabolic health
Best Price
at Lab Sourced
$104.67
$10.47/mg · 10mg
Buy at Lab Sourced
/ research index

The research base

Research Maturity
★★★★★
5/5 — Volume of studies
Evidence Strength
★★★★★
5/5 — Quality of evidence

200+ clinical trials. Strongest evidence base for weight research peptides. Works as researched.

/ mechanism of action

How it works

GLP-1 receptor agonist. Decreases appetite, slows gastric emptying, improves insulin sensitivity.

/ research dosing

Common research protocols

Range
0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg/week (FDA titration)
Frequency
Once weekly subcutaneous
Route
Subcutaneous abdomen, thigh, or upper arm
Cycle
Start 0.25mg/week × 4 weeks → 0.5mg/week × 4 weeks → continue escalating monthly to 2.4mg/week target
Research notes

Standard FDA titration schedule for Wegovy. Each dose held minimum 4 weeks before increase. GI side effects (nausea, constipation) most pronounced in first 2 weeks of each new dose. If missing dose: take within 5 days, otherwise skip to next scheduled week.

References
FDA Wegovy labelSTEP-1 NCT03548935PMID: 33567185
FOR RESEARCH USE ONLY. Doses listed are compiled from published research literature, FDA-approved drug labels, and well-documented research community practice. Not medical advice.
/ standalone use

As a solo compound

Strong standalone evidence. Most clinical trials test it alone.

/ side effects

What to know

Common: nausea (30%), GI adjustment. Usually resolve over time.

/ timeline

Realistic expectations

2-4 weeks for appetite suppression, 12+ weeks for significant changes

/ recommendation

Where to buy Semaglutide

🏆Our pick for Semaglutide
Valor Peptides
5mg · USA · Card / Crypto
  • Third-party tested (Janoshik)
  • COAs provided — Comprehensive
  • Highest verification tier in stock
  • 4.8★ community rating
$107.94$81.04
$16.21/mg
Buy at Valor Peptides
Also solid
Modern Research Peptides
5mg · $24.19/mg
$120.93
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Peptidology
10mg · $22.28/mg
$222.77
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AMP Peptides
10mg · $11.03/mg
$110.28
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/ all listings

Full index, price per mg

RefillPen
4.5
Size
10mg
Price
$104.60
$/mg
$10.46
Out of stock
Lab Sourced
4.7
Size
10mg
Price
$104.67
$/mg
$10.47
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AMP Peptides
4.8
Size
10mg
Price
$110.28
$/mg
$11.03
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Peppy
4.7
Size
10mg
Price
$111.09
$/mg
$11.11
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Throne
4.7
Size
10mg
Price
$113.73
$/mg
$11.37
Out of stock
Renova Peptides
4.6
Size
10mg
Price
$138.26
$/mg
$13.83
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Biocase Innovations
4.6
Size
10mg
Price
$140.01
$/mg
$14.00
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Ascension Peptides
4.8
Size
10mg
Price
$155.73
$/mg
$15.57
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Nano Blue Labs
4.6
Size
10mg
Price
$158.81
$/mg
$15.88
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Purus Peptides
4.7
Size
10mg
Price
$158.83
$/mg
$15.88
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AlgoRX
4.7
Size
10mg
Price
$160.97
$/mg
$16.10
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Felix Chemical Supply
4.5
Size
10mg
Price
$161.72
$/mg
$16.17
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Valor Peptides
4.8
Size
5mg
Price
$81.04
$/mg
$16.21
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Good Labs
4.7
Size
10mg
Price
$162.32
$/mg
$16.23
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EZ Peptides
4.7
Size
5mg
Price
$81.56
$/mg
$16.31
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Felix Chemical Supply
4.5
Size
5mg
Price
$86.74
$/mg
$17.35
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Molecular Solutions
4.7
Size
10mg
Price
$183.66
$/mg
$18.37
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Atomik Labz
4.7
Size
10mg
Price
$184.22
$/mg
$18.42
Out of stock
Welli Labs
4.6
Size
10mg
Price
$185.58
$/mg
$18.56
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FITSKNS
4.6
Size
5mg
Price
$102.36
$/mg
$20.47
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Flawless Compounds
4.7
Size
10mg
Price
$206.36
$/mg
$20.64
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Modified Aminos
4.5
Size
10mg
Price
$209.13
$/mg
$20.91
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Modified Aminos
4.5
Size
5mg
Price
$106.05
$/mg
$21.21
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RetaOneLabs
4.7
Size
5mg
Price
$107.80
$/mg
$21.56
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Valor Peptides
4.8
Size
10mg
Price
$216.18
$/mg
$21.62
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LA Peptides
4.6
Size
10mg
Price
$217.76
$/mg
$21.78
Out of stock
Glow Aminos
4.5
Size
10mg
Price
$220.09
$/mg
$22.01
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Ion Peptide
4.6
Size
10mg
Price
$222.39
$/mg
$22.24
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Peptidology
4.8
Size
10mg
Price
$222.77
$/mg
$22.28
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Renova Peptides
4.6
Size
5mg
Price
$112.47
$/mg
$22.49
Out of stock
Southern Aminos
4.6
Size
10mg
Price
$225.57
$/mg
$22.56
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EZ Peptides
4.7
Size
10mg
Price
$230.43
$/mg
$23.04
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Modern Research Peptides
4.8
Size
5mg
Price
$120.93
$/mg
$24.19
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Molecular Solutions
4.7
Size
5mg
Price
$121.11
$/mg
$24.22
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Glacier Aminos
4.6
Size
10mg
Price
$242.57
$/mg
$24.26
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Double R Labs
4.7
Size
10mg
Price
$243.06
$/mg
$24.31
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Solution Peptides
4.6
Size
10mg
Price
$244.91
$/mg
$24.49
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RetaOneLabs
4.7
Size
10mg
Price
$245.37
$/mg
$24.54
Out of stock
Modern Research Peptides
4.8
Size
10mg
Price
$247.44
$/mg
$24.74
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FITSKNS
4.6
Size
10mg
Price
$248.21
$/mg
$24.82
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Double R Labs
4.7
Size
5mg
Price
$125.83
$/mg
$25.17
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Ascension Peptides
4.8
Size
3mg
Price
$77.60
$/mg
$25.87
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Modern Research Peptides
4.8
Size
3mg
Price
$78.59
$/mg
$26.20
Out of stock
Double R Labs
4.7
Size
3mg
Price
$79.48
$/mg
$26.49
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AlgoRX
4.7
Size
3mg
Price
$84.13
$/mg
$28.04
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Throne
4.7
Size
5mg
Price
$140.62
$/mg
$28.12
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Ion Peptide
4.6
Size
3mg
Price
$86.55
$/mg
$28.85
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Peppy
4.7
Size
5mg
Price
$144.74
$/mg
$28.95
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Atomik Labz
4.7
Size
3mg
Price
$87.42
$/mg
$29.14
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Nano Blue Labs
4.6
Size
5mg
Price
$149.61
$/mg
$29.92
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Valor Peptides
4.8
Size
3mg
Price
$90.15
$/mg
$30.05
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Glow Aminos
4.5
Size
3mg
Price
$93.67
$/mg
$31.22
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Biocase Innovations
4.6
Size
5mg
Price
$156.38
$/mg
$31.28
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Glow Aminos
4.5
Size
5mg
Price
$161.83
$/mg
$32.37
Out of stock
Welli Labs
4.6
Size
5mg
Price
$162.91
$/mg
$32.58
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AlgoRX
4.7
Size
5mg
Price
$163.34
$/mg
$32.67
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Purus Peptides
4.7
Size
5mg
Price
$164.80
$/mg
$32.96
Out of stock
Glacier Aminos
4.6
Size
5mg
Price
$165.57
$/mg
$33.11
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Molecular Solutions
4.7
Size
3mg
Price
$100.99
$/mg
$33.66
Out of stock
Good Labs
4.7
Size
5mg
Price
$168.48
$/mg
$33.70
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Southern Aminos
4.6
Size
5mg
Price
$178.37
$/mg
$35.67
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Peptidology
4.8
Size
5mg
Price
$180.88
$/mg
$36.18
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Lab Sourced
4.7
Size
3mg
Price
$108.98
$/mg
$36.33
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Throne
4.7
Size
3mg
Price
$109.71
$/mg
$36.57
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LA Peptides
4.6
Size
5mg
Price
$183.47
$/mg
$36.69
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Peppy
4.7
Size
3mg
Price
$112.54
$/mg
$37.51
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Lab Sourced
4.7
Size
5mg
Price
$189.77
$/mg
$37.95
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Flawless Compounds
4.7
Size
5mg
Price
$191.52
$/mg
$38.30
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Flawless Compounds
4.7
Size
3mg
Price
$115.58
$/mg
$38.53
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AMP Peptides
4.8
Size
5mg
Price
$194.87
$/mg
$38.97
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Biocase Innovations
4.6
Size
3mg
Price
$117.18
$/mg
$39.06
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Southern Aminos
4.6
Size
3mg
Price
$117.23
$/mg
$39.08
Out of stock
Ascension Peptides
4.8
Size
5mg
Price
$199.13
$/mg
$39.83
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RefillPen
4.5
Size
5mg
Price
$204.21
$/mg
$40.84
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Atomik Labz
4.7
Size
5mg
Price
$204.91
$/mg
$40.98
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Ion Peptide
4.6
Size
5mg
Price
$205.62
$/mg
$41.12
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Modified Aminos
4.5
Size
3mg
Price
$125.32
$/mg
$41.77
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Solution Peptides
4.6
Size
5mg
Price
$208.91
$/mg
$41.78
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Welli Labs
4.6
Size
3mg
Price
$128.53
$/mg
$42.84
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RetaOneLabs
4.7
Size
3mg
Price
$132.37
$/mg
$44.12
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Glacier Aminos
4.6
Size
3mg
Price
$138.63
$/mg
$46.21
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EZ Peptides
4.7
Size
3mg
Price
$139.00
$/mg
$46.33
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Nano Blue Labs
4.6
Size
3mg
Price
$139.77
$/mg
$46.59
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AMP Peptides
4.8
Size
3mg
Price
$149.07
$/mg
$49.69
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Purus Peptides
4.7
Size
3mg
Price
$155.81
$/mg
$51.94
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Good Labs
4.7
Size
3mg
Price
$160.47
$/mg
$53.49
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Renova Peptides
4.6
Size
3mg
Price
$179.91
$/mg
$59.97
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Peptidology
4.8
Size
3mg
Price
$184.27
$/mg
$61.42
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RefillPen
4.5
Size
3mg
Price
$192.55
$/mg
$64.18
Out of stock
Felix Chemical Supply
4.5
Size
3mg
Price
$197.19
$/mg
$65.73
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FITSKNS
4.6
Size
3mg
Price
$200.73
$/mg
$66.91
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Solution Peptides
4.6
Size
3mg
Price
$203.37
$/mg
$67.79
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LA Peptides
4.6
Size
3mg
Price
$208.41
$/mg
$69.47
Out of stock
FOR RESEARCH USE ONLY. Semaglutide is intended for laboratory research and not for human consumption.