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The incretin class — GLP-1, GLP-1/GIP, and triple agonists. Ranked roughly by potency in current trials. All require careful titration; see each protocol.

01
R
Retatrutide (GLP-3)
★★★★★ 5/5 research
Protocol snapshot
Dose2 → 4 → 6 → 8 → 12 mg/week (titration ladder)
FrequencyOnce weekly subcutaneous
CycleStart at 2mg/week × 4 weeks → escalate by 2-4mg every 4 weeks → maintenance at 8-12mg/week
Full protocol + references →
🏆Our pick for Retatrutide (GLP-3)
Ascension Peptides
30mg · USA · Card / Crypto / Zelle
  • Third-party tested (Janoshik)
  • COAs provided — Per-batch core, quarterly bonus
  • Best $/mg in stock right now
  • 4.8★ community rating
$269.99$175.00
$2.62/mg
Buy at Ascension Peptides
Affiliate link · disclosure
Also solid
AMP Peptides
48mg · $4.48/mg
$215.00
Buy →
Double R Labs
30mg · $3.68/mg
$129.99
Buy →
Welli Labs
20mg · $4.75/mg
$94.99
Buy →
02
T
Tirzepatide
★★★★★ 5/5 research
Protocol snapshot
Dose2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg/week (FDA titration)
FrequencyOnce weekly subcutaneous
CycleStart 2.5mg/week × 4 weeks → escalate by 2.5mg every 4 weeks → maintenance at 10-15mg/week
Full protocol + references →
🏆Our pick for Tirzepatide
Ascension Peptides
30mg · USA · Card / Crypto / Zelle
  • Third-party tested (Janoshik)
  • COAs provided — Per-batch core, quarterly bonus
  • Best $/mg in stock right now
  • 4.8★ community rating
$199.99$98.00
$1.47/mg
Buy at Ascension Peptides
Affiliate link · disclosure
Also solid
AMP Peptides
60mg · $2.80/mg
$168.00
Buy →
Double R Labs
60mg · $1.54/mg
$109.00
Buy →
Welli Labs
60mg · $2.08/mg
$124.99
Buy →
03
S
Semaglutide
★★★★★ 5/5 research
Protocol snapshot
Dose0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg/week (FDA titration)
FrequencyOnce weekly subcutaneous
CycleStart 0.25mg/week × 4 weeks → 0.5mg/week × 4 weeks → continue escalating monthly to 2.4mg/week target
Full protocol + references →
🏆Our pick for Semaglutide
Ascension Peptides
5mg · USA · Card / Crypto / Zelle
  • Third-party tested (Janoshik)
  • COAs provided — Per-batch core, quarterly bonus
  • Highest verification tier in stock
  • 4.8★ community rating
$99.99$40.00
$3.60/mg
Buy at Ascension Peptides
Affiliate link · disclosure
Also solid
AMP Peptides
10mg · $5.40/mg
$54.00
Buy →
Double R Labs
5mg · $4.25/mg
$24.99
Buy →
Welli Labs
20mg · $2.25/mg
$44.99
Buy →
04
A
AOD-9604
★★★★★ 3/5 research
Protocol snapshot
Dose300-500 mcg/day
FrequencyOnce daily, AM on empty stomach
Cycle4-12 weeks continuous
Full protocol + references →
🏆Our pick for AOD-9604
Ascension Peptides
5mg · USA · Card / Crypto / Zelle
  • Third-party tested (Janoshik)
  • COAs provided — Per-batch core, quarterly bonus
  • Best $/mg in stock right now
  • 4.8★ community rating
$74.99$55.00
$4.95/mg
Buy at Ascension Peptides
Affiliate link · disclosure
Also solid
AMP Peptides
2mg · $19.00/mg
$38.00
Buy →
Atomik Labz
5mg · $7.80/mg
$39.00
Buy →
Valor Peptides
10mg · $9.35/mg
$93.51
Buy →

For research use only. Rankings reflect our source-verification methodology and current research maturity — not medical advice.